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Protein Purification Associate Scientist

GenScript/ProBio
locationPiscataway, NJ 08854, USA
PublishedPublished: 6/14/2022
Science
Full Time

Job Description

Job DescriptionAbout GenScriptGenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology.About ProBioProBio proactively provides end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy, vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers. ProBio's total cell and gene therapy solution covers CMC of plasmid and virus for IND filing as well as clinical manufacturing and commercial manufacturing.

Job Summary:

We are seeking a skilled and detail-oriented Protein Purification Associate Scientist to join our US Protein Department. This role involves executing downstream processing activities including protein purification, characterization, and documentation. The ideal candidate will have a solid background in biochemistry, biotechnology, or a related field, along with hands-on experience in protein purification techniques in a laboratory or manufacturing setting.

Key Responsibilities:

  1. Perform protein purification using a variety of chromatography techniques such as affinity, ion exchange, size exclusion, and hydrophobic interaction.
  2. Prepare buffers and reagents following SOPs and project-specific protocols.
  3. Characterize protein products using SDS-PAGE, Western Blot, HPLC, UV spectroscopy, BCA assay, and other analytical methods.
  4. Maintain accurate, complete, and timely documentation of experimental procedures and results.
  5. Troubleshoot and optimize purification protocols as needed to improve yield and purity.
  6. Collaborate closely with upstream, analytical, and quality teams to ensure project timelines and specifications are met.
  7. Assist in the revision and creation of SOPs, batch records, and technical reports.
  8. Support additional tasks and projects as assigned by the department supervisor.

Qualifications:

  1. BS/MS in Molecular Biology, Cellular Biology, Biochemistry or related field with 1+ years of relevant experience in protein purification/characterization.
  2. Familiarity with AKTA systems and chromatography software is a strong plus.
  3. Strong organizational and documentation skills, with attention to detail and data integrity.
  4. Ability to work independently and as part of a team in a fast-paced environment.
  5. Excellent problem-solving and communication skills.
  6. Experience in a CRO or CDMO setting is preferred.

#GS

GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.

Please note: Genscript USA Inc./ProBio Inc. will only contact candidates through verified application sources. GenScript/Probio does not request personal information from candidates through individual email or any other platform.

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